True about scoline are following except –
## **Core Concept**
Scoline, also known as succinylcholine, is a depolarizing neuromuscular blocking agent used in anesthesia to facilitate endotracheal intubation and provide muscle relaxation during surgery or mechanical ventilation. It acts by mimicking the action of acetylcholine at the nicotinic receptors of the neuromuscular junction, leading to initial muscle depolarization and then prolonged paralysis.
## **Why the Correct Answer is Right**
The correct answer, , implies that one of the provided statements about succinylcholine is not true. Succinylcholine is known for its rapid onset and short duration of action. It is metabolized by plasma cholinesterase. A key characteristic is its ability to cause hyperkalemia due to muscle depolarization, and it can also increase intraocular pressure and intragastric pressure.
## **Why Each Wrong Option is Incorrect**
- **Option A:** If a statement suggests that succinylcholine has a rapid onset of action, it would be true. Succinylcholine is known for its quick onset, making it ideal for rapid sequence induction.
- **Option B:** If a statement mentions that succinylcholine is metabolized by plasma cholinesterase, it would be true. This is a correct statement regarding its pharmacokinetics.
- **Option C:** If a statement indicates that succinylcholine can cause hyperkalemia, it would be true. This is a well-known side effect, particularly in patients with certain conditions like burns or trauma.
- **Option D:** Without the specific details of each option, we can infer that the incorrect statement might relate to a characteristic not typically associated with succinylcholine, such as prolonged duration of action, lack of effect on intraocular pressure, or metabolism by another enzyme.
## **Clinical Pearl / High-Yield Fact**
A critical point to remember about succinylcholine is its potential to cause **hyperkalemia**, especially in patients with burns, trauma, or neuromuscular diseases. This side effect can be life-threatening and is a key consideration when deciding to use this medication.
## **Correct Answer: D.**