True about membranous GN are following except
Correct Answer: Deposition between endothelium and B.M.
Description: Ans. is 'b' i.e., Deposition between endothelium and B.M.Membranous glomerulonephritis o Membranous glomerulonephritis, also known as membranous nephropathy, is a slowly progressive disease of the kidney affecting mostly patients between ages of 30 and 50 years.o Membranous glomerulonephritis is classifiedPrimary (idiopathic) - 85%Secondary - 15% Drugs --> Penicillamine, captopril, gold, NSAIDS Malignant tumors --> Lung, colon, melanoma Auto immune conditions --> SLE, thyroiditis Infections HBC, HCV, syphilis, schistosomiasis, malariaMembranous glomerulonephritis is characterized by ?o Diffuse thickening of glomerular capillary wall.o Accumulation of electron - dense, immunoglobulin containing deposits along subepithelial side (between epithelium and GBM).o Membranous glomerulonephritis is the most common cause of nephrotic syndrome in adults.
Category:
Pathology
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