**Core Concept**
Minimal change disease (MCD) is a type of nephrotic syndrome characterized by the loss of foot processes of podocytes, leading to massive proteinuria. Light microscopy in MCD typically shows normal-appearing glomeruli, which can make diagnosis challenging.

**Why the Correct Answer is Right**
The hallmark of MCD is the preservation of the glomerular architecture on light microscopy, despite the presence of massive proteinuria. This is because the disease primarily affects the podocytes, which can only be visualized with electron microscopy. The lack of visible changes on light microscopy is due to the fact that the foot processes of podocytes appear normal, but are actually effaced and fused.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because MCD is not typically associated with the presence of crescents, which are a hallmark of more severe glomerulonephritis.
**Option B:** This option is incorrect because the glomeruli in MCD appear normal on light microscopy, not sclerotic.
**Option C:** This option is incorrect because the presence of immune complexes is more characteristic of membranous nephropathy, not MCD.

**Clinical Pearl / High-Yield Fact**
It's worth noting that the diagnosis of MCD is often made based on the clinical presentation and response to corticosteroids, rather than histological findings. Patients with MCD typically respond well to corticosteroid therapy, which can induce remission and reduce proteinuria.

**Correct Answer:** B. Normal-appearing glomeruli on light microscopy are characteristic of minimal change disease.