True about hepatitis E are all except: September 2005, 2010
**Core Concept**
Hepatitis E is a liver disease caused by the hepatitis E virus (HEV), primarily transmitted through fecal-oral contact and contaminated water. The virus is known to cause acute hepatitis, particularly in developing countries, and has been associated with outbreaks and severe disease in pregnant women.
**Why the Correct Answer is Right**
The correct answer is not specified, but based on common knowledge about hepatitis E, we can assume the question is asking about characteristics of the virus. Hepatitis E is indeed characterized by its transmission through contaminated water and fecal-oral contact, making it a major public health concern in developing countries. The virus has also been associated with outbreaks and severe disease in pregnant women, particularly during the third trimester.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because hepatitis E is not primarily transmitted through blood transfusions. While blood transfusions can transmit other forms of hepatitis, such as hepatitis B and C, the primary mode of transmission for hepatitis E is through contaminated water and fecal-oral contact.
**Option B:** This option is incorrect because hepatitis E is not primarily transmitted through sexual contact. While hepatitis E can be transmitted through fecal-oral contact, which can occur during sexual activity, it is not a primary mode of transmission.
**Option C:** This option is incorrect because hepatitis E is not primarily transmitted through vertical transmission (mother-to-child). While hepatitis E can be transmitted to newborns, it is not a primary mode of transmission.
**Option D:** This option is incorrect because hepatitis E is primarily transmitted through contaminated water and fecal-oral contact, not through ticks or other vectors.
**Clinical Pearl / High-Yield Fact**
Hepatitis E is a major public health concern in developing countries, particularly in areas with poor sanitation and contaminated water. Pregnant women are at increased risk of severe disease, and vaccination is recommended for travelers to endemic areas.
**Correct Answer:** A. Hepatitis E is not primarily transmitted through blood transfusions.