True about Glutathione –
**Core Concept**
Glutathione is a tripeptide antioxidant composed of glutamic acid, cysteine, and glycine. It plays a crucial role in cellular defense mechanisms, particularly in detoxifying reactive oxygen species (ROS) and maintaining the redox balance within cells.
**Why the Correct Answer is Right**
Glutathione's antioxidant properties are attributed to the sulfhydryl group (-SH) of cysteine, which can donate electrons to neutralize ROS. This process is facilitated by the enzyme glutathione peroxidase, which uses glutathione as a cofactor to reduce hydrogen peroxide (H2O2) and other peroxides. The reduced form of glutathione (GSH) is then replenished by the enzyme glutathione reductase.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided.
**Option B:** Without more information, it's difficult to assess the validity of this option.
**Option C:** This option is not provided.
**Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
Glutathione deficiency has been implicated in various diseases, including oxidative stress-related disorders, cancer, and neurodegenerative conditions. Supplementing with glutathione precursors, such as N-acetyl cysteine (NAC), may help maintain glutathione levels and alleviate oxidative stress.
**Correct Answer:** Not provided in the initial prompt.