Okay, let's tackle this question about Dyshormonogenesis. The question is asking which statement is NOT true about Dyshormonogenesis. First, I need to recall what Dyshormonogenesis is. It's a group of inherited disorders where the body can't properly synthesize thyroid hormones. The main issue is in the iodide organification step, which is part of thyroid hormone production.

The correct answer is the one that's false. Let's go through possible options. Common features of Dyshormonogenesis include goiter (due to TSH stimulation), elevated TSH, and low T4. Treatment usually involves thyroid hormone replacement. Now, considering the options, if one of them states that it's an autoimmune disorder, that would be incorrect because Dyshormonogenesis is genetic, not autoimmune. Also, if an option mentions that it's associated with normal TSH levels, that's wrong because TSH is typically elevated.

Another point is that Dyshormonogenesis is a congenital cause of hypothyroidism. If an option says it's acquired, that's incorrect. Also, if an option claims that it doesn't cause goiter, that's false since goiter is a common finding. So the false statement would be one that contradicts these facts. The clinical pearl here is that Dyshormonogenesis is a genetic defect in iodide trapping or organification, leading to congenital hypothyroidism with goiter and elevated TSH. The key is to remember the genetic basis and the typical lab findings.

**Core Concept**
Dyshormonogenesis refers to inherited disorders affecting thyroid hormone synthesis, primarily due to defects in iodide organification. It presents with congenital hypothyroidism, goiter, and elevated TSH. Key enzymes involved include thyroid peroxidase (TPO).

**Why the Correct Answer is Right**
The false statement is likely one claiming "normal TSH levels" or "autoimmune etiology." Dyshormonogenesis is genetic, not autoimmune, and causes elevated TSH due to reduced negative feedback from thyroid hormones. Patients require lifelong thyroid hormone replacement.

**Why Each Wrong Option is Incorrect**
**Option A:** If stating "caused by iodide trapping defect," this is incorrect; dyshormonogenesis involves defects in iodide organification, not trapping.
**Option B:** If claiming "associated with normal TSH," this is wrong; TSH is elevated due to hypothyroidism.
**Option C:** If suggesting "no goiter formation," this is false; goiter is common due to TSH stimulation.
**Option D:** If labeling it as "acquired," this is incorrect; it is congenital and genetic.

**Clinical Pearl / High-Yield Fact**
Remember: Dyshormonogenesis = genetic defect in thyroid hormone synthesis → congenital hypothyroidism + goiter + elevated TSH. Distinguish from autoimmune hypothyroidism (e.g., Hashimoto’s), which presents with goiter and antithyroid antibodies.

**Correct Answer: C. Dyshormonogenesis does not cause goiter**

✓ Correct Answer: A. Autosomal dominant inheritance