True about conversion of 20C fatty acid conversion to prostaglandin synthase
Correct Answer: The primary prostaglandin is PG H2
Description: Biosynthesis of Prostaglandins Prostaglandins are derived from the PUFA, the three series being derived from the following fatty acids. 1 series (1 double bond) -from Linoleic acid 2 series (2 double bonds)-from Arachidonic acid 3 series (3 double bonds)-Eicosa Penta-enoic Naturally occurring PGs belong to the 2 series. i. PGs are not stored as such; the precursor fatty acids are stored in membrane as phospholipids. The arachidonic acid is released by the action of phospholipase A2 on phospholipids (Fig. 13.3). ii. Synthesis is catalyzed by Prostaglandin H synthase (PGHS). It contains two separate enzyme activities, cyclo-oxygenase, and peroxidase. iii. PGG2 and PGH2 are formed as intermediates during the synthesis of other PGs. Specific enzymes conve PGH2 to other prostaglandinsRef: DM Vasudevan - Textbook of Biochemistry, 8th edition, page no: 164
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now