True about congenital Rubella syndrome is:-
**Core Concept**
Congenital Rubella syndrome (CRS) is a condition that occurs in infants born to mothers infected with Rubella virus during pregnancy, particularly during the first trimester. This condition is characterized by a range of congenital abnormalities and health problems, resulting from the virus's interference with fetal development.
**Why the Correct Answer is Right**
The correct answer is related to the pathophysiology of Congenital Rubella syndrome. Rubella virus infects the fetus through the placenta, leading to a range of congenital abnormalities. The virus affects the development of the fetus, particularly during the first trimester, when organogenesis is taking place. This results in a range of health problems, including deafness, cataracts, heart defects, and intellectual disability.
**Why Each Wrong Option is Incorrect**
**Option A:** While it is true that Congenital Rubella syndrome can cause a range of health problems, including deafness and cataracts, this option is too vague and does not specifically address the pathophysiology of CRS.
**Option B:** This option is incorrect as Congenital Rubella syndrome is not typically associated with an increase in birth weight. In fact, infants with CRS are often born with low birth weight.
**Option C:** This option is incorrect as Congenital Rubella syndrome is not typically associated with an increase in birth length. In fact, infants with CRS are often born with short stature.
**Clinical Pearl / High-Yield Fact**
It is essential to note that Congenital Rubella syndrome can be prevented through vaccination, particularly in pregnant women. Rubella vaccination is a crucial public health measure to prevent CRS and its associated health problems.
**Correct Answer:** D