True about coding strand of DNA
**Core Concept**
The coding strand of DNA is a crucial concept in molecular biology, where one strand serves as a template for RNA synthesis during transcription. The coding strand has the same sequence as the final RNA product, except for the substitution of uracil (U) for thymine (T).
**Why the Correct Answer is Right**
The coding strand is also known as the sense strand, and it contains the genetic information that will be used to synthesize a complementary RNA molecule. During transcription, RNA polymerase reads the template strand and matches the incoming nucleotides to the base pairing rules (A-T and G-C). The coding strand, being complementary to the template strand, has the same sequence as the final RNA product, except for the substitution of uracil (U) for thymine (T).
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not provided, but it is likely a distractor that might confuse the student with the concept of the non-coding strand or the template strand.
* **Option B:** This option might be incorrect because it could refer to the non-coding strand, which is complementary to the coding strand but does not contain the genetic information for protein synthesis.
* **Option C:** This option might be incorrect because it could refer to the template strand, which is complementary to the coding strand but is not the final RNA product.
* **Option D:** This option is not provided, but it could be a distractor that refers to a different concept in molecular biology.
**Clinical Pearl / High-Yield Fact**
The coding strand and the template strand are complementary to each other, but only the coding strand contains the genetic information that will be used to synthesize a complementary RNA molecule. This concept is crucial for understanding the process of transcription and the synthesis of RNA molecules from DNA.
**Correct Answer: C. The template strand.**