Triple Marker test includes :
**Core Concept**
The Triple Marker test, also known as the Triple Screen, is a prenatal test used to detect certain fetal abnormalities. It measures levels of **alpha-fetoprotein (AFP)**, **estriol**, and **human chorionic gonadotropin (hCG)** in the maternal blood.
**Why the Correct Answer is Right**
The Triple Marker test is designed to screen for potential genetic disorders, such as **Down syndrome**, **trisomy 18**, and **neural tube defects**. Elevated or decreased levels of these markers can indicate an increased risk of these conditions. For example, low levels of **estriol** and **AFP** and high levels of **hCG** may suggest **Down syndrome**.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it is not specified.
**Option B:** Incorrect because it is not specified.
**Option D:** Incorrect because it is not specified.
**Clinical Pearl / High-Yield Fact**
The Triple Marker test is typically performed between 15 and 20 weeks of gestation. It is essential to remember that this test is a screening tool, not a diagnostic test, and abnormal results should be followed up with more specific diagnostic tests.
**Correct Answer:** D. AFP, hCG, and Estriol