**Question:** Treatment of dhatura poisoning is done with: NEET 15

**Core Concept:** Dhatura, also known as Jimsonweed, is a toxic plant that contains cardiac glycosides, which can cause life-threatening cardiac arrhythmias and other complications upon ingestion.

**Why the Correct Answer is Right:** The correct treatment for dhatura poisoning involves the use of antidotes that neutralize the toxic effects of cardiac glycosides. In this case, the correct answer is D, which refers to **Digoxin Immune Fab (O)** (Digoxin Antibody Fab fragment).

Digoxin Immune Fab is a monoclonal antibody fragment that binds to digoxin, a cardiac glycoside that accumulates in the heart after dhatura poisoning. By binding to digoxin, Digoxin Immune Fab neutralizes its toxic effects, preventing further cardiac arrhythmias and other complications.

**Why Each Wrong Option is Incorrect:**

A. **Digoxin:** Although digoxin is a cardiac glycoside, it is not an antidote for dhatura poisoning. In fact, it would exacerbate the problem by increasing cardiac glycoside levels in the body.

B. **Supportive Care:** While supportive care is essential in managing the patient's symptoms, it does not specifically target the toxic cardiac glycosides present in dhatura poisoning.

C. **Activated Charcoal:** Activated charcoal is primarily used for poisoning caused by ingestion of other substances, not cardiac glycosides. It does not neutralize the cardiac glycosides in dhatura poisoning.

**Clinical Pearls:** In cases of dhatura poisoning, it is crucial to administer Digoxin Immune Fab (Option D) as soon as possible to prevent cardiac toxicity and its severe consequences. Supportive care, including monitoring vital signs, maintaining electrolyte balance, and managing complications, is also essential.

**Correct Answer:** **Digoxin Immune Fab (D)**

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