## **Core Concept**
Cytomegalovirus (CMV) retinitis is a serious viral eye infection that can cause blindness in individuals with weakened immune systems, particularly those with AIDS. The treatment of CMV retinitis in AIDS patients involves antiviral medications that specifically target CMV.
## **Why the Correct Answer is Right**
The correct answer, **Ganciclovir**, is a potent antiviral medication used to treat CMV infections. Ganciclovir works by inhibiting viral DNA synthesis, thereby preventing the replication of CMV. It can be administered intravenously, orally, or via an intravitreal implant, making it effective for treating CMV retinitis. Another antiviral drug, **Valganciclovir** (an oral prodrug of ganciclovir), is also used, especially for maintenance therapy.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is blank and cannot be evaluated.
- **Option B:** This option is blank and cannot be evaluated.
- **Option D:** This option is blank and cannot be evaluated.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that CMV retinitis is an AIDS-defining illness. The introduction of antiretroviral therapy (ART) has significantly reduced the incidence of CMV retinitis in AIDS patients by improving immune function. However, in areas with limited access to ART or in cases of ART failure, CMV retinitis remains a concern.
## **Correct Answer:** . **Ganciclovir**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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