Treatment of cholestasis during pregnancy is all except-
**Core Concept**
Cholestasis of pregnancy is a condition characterized by impaired bile flow, leading to elevated bile acids in the blood. It is a significant concern during pregnancy due to the risk of preterm labor and fetal distress.
**Why the Correct Answer is Right**
The primary goal of treatment is to alleviate symptoms and prevent complications. Ursodeoxycholic acid (UDCA) is a bile acid that can help improve bile flow and reduce bile acid levels. It is considered the first-line treatment for cholestasis of pregnancy. UDCA works by increasing the expression of genes involved in bile acid synthesis, reducing the levels of bile acids in the blood, and improving liver function.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not a standard treatment for cholestasis of pregnancy. While it may be used in other liver conditions, it is not the preferred treatment for this specific condition.
**Option B:** This option is not a recommended treatment for cholestasis of pregnancy. In fact, it may worsen the condition by increasing the levels of bile acids in the blood.
**Option C:** This option is not a standard treatment for cholestasis of pregnancy. While it may be used in other conditions, it is not the preferred treatment for this specific condition.
**Clinical Pearl / High-Yield Fact**
UDCA is a bile acid that can help improve bile flow and reduce bile acid levels in the blood, making it an essential treatment for cholestasis of pregnancy. It is essential to note that UDCA should be used under the guidance of a healthcare provider, as it may have side effects and interact with other medications.
**Correct Answer:** D.