**Core Concept**
The treatment of depression, especially in cases involving suicidal attempts, requires a comprehensive approach focusing on **mood stabilizers**, **antidepressants**, and **psychological support**. The primary goal is to ensure the patient's safety while effectively managing their depressive symptoms. **Selective serotonin reuptake inhibitors (SSRIs)** are often considered due to their relatively favorable side-effect profile.

**Why the Correct Answer is Right**
Given the context, the most appropriate choice would involve medications that can be used urgently and have a relatively rapid onset of action, alongside therapies that address the immediate risk of suicide. **Lithium** and **SSRIs** are commonly used, but in urgent cases, especially with suicidal ideation, ensuring the patient's safety is paramount, which might involve hospitalization and close monitoring.

**Why Each Wrong Option is Incorrect**
**Option A:** Might not be the best choice if it doesn't include a combination of therapies.
**Option B:** Could be incorrect if it suggests a single medication without considering the need for immediate intervention.
**Option C:** Might be wrong if it doesn't prioritize the patient's immediate safety.
**Option D:** Could be incorrect if the option does not include a comprehensive treatment plan.

**Clinical Pearl / High-Yield Fact**
In patients with depression and a history of suicidal attempts, **close monitoring** and a **multidisciplinary approach** are crucial. The treatment should aim at reducing suicidal ideation quickly and effectively managing depression.

**Correct Answer:** D. Electroconvulsive therapy (ECT) is often considered the treatment of choice for severe depression, especially in cases with suicidal ideation, due to its rapid onset of action.