**Core Concept**
Clostridial myonecrosis, also known as gas gangrene, is a severe and potentially life-threatening infection caused by Clostridium species, particularly Clostridium perfringens. This condition results from the production of toxins, including alpha toxin, which causes tissue necrosis and gas production.

**Why the Correct Answer is Right**
The treatment for clostridial myonecrosis involves surgical debridement of the affected tissue to remove the source of the infection, along with administration of antibiotics to target the causative bacteria. The antibiotic of choice is typically a penicillin or a combination of penicillin and clindamycin, as Clostridium species are often resistant to beta-lactamase-producing bacteria.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because antivenom is not indicated in the treatment of clostridial myonecrosis, as the infection is caused by bacterial toxins rather than snake venom.
**Option B:** This option is incorrect because hyperbaric oxygen therapy may be beneficial in certain cases of gas gangrene, but it is not the primary treatment for clostridial myonecrosis.
**Option C:** This option is incorrect because supportive care, such as fluid resuscitation and monitoring, is essential in the management of clostridial myonecrosis, but it is not the primary treatment.

**Clinical Pearl / High-Yield Fact**
The use of clindamycin in combination with penicillin is essential in the treatment of clostridial myonecrosis, as clindamycin inhibits protein synthesis in bacteria, thereby reducing the production of toxins.

**Correct Answer: D. Administration of penicillin and surgical debridement of the affected tissue.**