**Core Concept**
Bipolar disorder is a chronic mental health condition characterized by episodes of mania, hypomania, or depression. Treatment aims to stabilize mood, manage symptoms, and improve quality of life. Various pharmacological agents are used to achieve these goals.

**Why the Correct Answer is Right**
The management of bipolar disorder involves a range of medications, including mood stabilizers, antipsychotics, and antidepressants. Mood stabilizers, such as lithium and valproate, help regulate mood swings. Antipsychotics, like olanzapine and quetiapine, are used for acute mania or as maintenance therapy. Antidepressants, however, are often used with caution due to the risk of inducing mania or rapid cycling.

**Why Each Wrong Option is Incorrect**
**Option A:** Lithium is a commonly used mood stabilizer in bipolar disorder treatment.
**Option B:** Valproate is another effective mood stabilizer for managing bipolar symptoms.
**Option C:** Olanzapine is an atypical antipsychotic used for treating acute mania and maintenance therapy in bipolar disorder.

**Clinical Pearl / High-Yield Fact**
It's essential to note that antidepressants should be used cautiously in bipolar disorder, as they can trigger mania or rapid cycling. A thorough risk-benefit assessment and monitoring are crucial when prescribing antidepressants in this context.

**Correct Answer: D.**