**Core Concept**
Desmoid tumors, also known as aggressive fibromatoses, are rare, benign, but locally aggressive neoplasms that arise from the deep connective tissue. They can occur at any age and are more common in females. Due to their potential for local invasion and recurrence, effective treatment is crucial to prevent complications and improve quality of life.

**Why the Correct Answer is Right**
The treatment of choice for desmoid tumors often involves a combination of surgery and radiotherapy. Surgery aims to achieve complete resection of the tumor, while radiotherapy is used to prevent recurrence by targeting any remaining microscopic disease. The combination of these two modalities has been shown to improve local control rates and reduce the risk of recurrence. In addition, radiotherapy can be used to treat tumors that are not amenable to surgical resection or in cases where surgical margins are positive.

**Why Each Wrong Option is Incorrect**
**Option A:** Surgery alone may not be sufficient for desmoid tumors, as they have a high rate of local recurrence. While surgery can provide temporary control, it often leads to further recurrences.

**Option B:** Chemotherapy is not a standard treatment for desmoid tumors, as their response to systemic therapy is generally poor. Chemotherapy may be considered in cases of metastatic disease or as part of a clinical trial.

**Option C:** Radiotherapy alone may not be sufficient to control desmoid tumors, as they are often resistant to radiation therapy. While radiotherapy can be used to treat recurrent tumors, it is typically used in combination with surgery.

**Clinical Pearl / High-Yield Fact**
It is essential to note that desmoid tumors are often associated with familial adenomatous polyposis (FAP) and other genetic syndromes. Patients with a family history of FAP or other genetic disorders should be evaluated for desmoid tumors, and a multidisciplinary approach should be considered for treatment.

**Correct Answer Line**
✓ Correct Answer: D. Surgery + Radiotherapy