**Core Concept**
The transurethral resection of the prostate (TURP) procedure involves the use of an irrigating fluid to maintain visibility and cool the resectoscope during the surgery. The choice of irrigant is crucial to prevent complications such as TUR syndrome, which can be life-threatening.
**Why the Correct Answer is Right**
The correct answer is **Glucose**. Glucose is not used as an irrigant in TURP due to its high osmolarity, which can lead to fluid overload and TUR syndrome. This is because glucose is rapidly absorbed into the bloodstream, causing an increase in osmolality and potentially leading to cerebral and pulmonary edema. Instead, isotonic irrigants such as glycine or sorbitol are commonly used.
**Why Each Wrong Option is Incorrect**
* **Option A:** Glycine is actually a commonly used irrigant in TURP, as it is non-toxic and has a low pH, which helps to prevent bleeding.
* **Option B:** Sorbitol is also a suitable irrigant in TURP, as it is non-toxic and has an osmotic pressure close to that of blood.
* **Option D:** **(Missing option)**
**Clinical Pearl / High-Yield Fact**
To remember the irrigants used in TURP, the mnemonic "GLYCINE" can be used, with each letter standing for a key characteristic: G - Glycine, L - Low osmolarity, Y - Yellow color, C - Cooling effect, I - Iso-osmotic, N - Non-toxic, E - Effective visibility.
**Correct Answer:** D.
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