**Core Concept**
The glucose transporter present in beta cells of the pancreas plays a crucial role in glucose sensing and insulin secretion. The beta cells detect the increase in blood glucose levels by taking up glucose through a specific glucose transporter, which triggers insulin release.
**Why the Correct Answer is Right**
The correct glucose transporter in beta cells is GLUT2. It is a facilitated diffusion transporter that allows glucose to enter the beta cells in response to high blood glucose levels. GLUT2 has a high Km for glucose, which means it is highly sensitive to changes in blood glucose levels, making it ideal for glucose sensing in beta cells. The presence of GLUT2 in beta cells enables them to detect glucose levels and regulate insulin secretion accordingly.
**Why Each Wrong Option is Incorrect**
**Option A:** GLUT1 is present in red blood cells and is responsible for maintaining glucose levels in the blood. It is not present in beta cells.
**Option B:** GLUT3 is present in neurons and is responsible for high-affinity glucose uptake. It is not present in beta cells.
**Option C:** GLUT4 is present in adipose tissue and skeletal muscle and is responsible for insulin-regulated glucose uptake. It is not present in beta cells.
**Clinical Pearl / High-Yield Fact**
GLUT2 is also present in the liver and small intestine, where it plays a role in glucose sensing and regulation of glucose metabolism.
**Correct Answer:** C. GLUT2.
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