Transmination of Aspaate forms ?
Correct Answer: Oxaloacetate
Description: Ans. is 'c' i.e., Oxaloacetate Transamination Transamination involves the reversible transfer of a-amino group of a-amino acid to an a-keto acid(' to form a new amino acid and a new keto acid. The enzyme catalyze the reaction is called aminotransferase (transaminase). Most transaminases use a-ketoglutarate (a-keto acid) as a common acceptor of a-amino group of a-amino acids. All transaminases require pyridoxal phosphate (Vitamin B6) as a coenzymneQ. Some of the most impoant transaminases are : -Alanine transaminase (ALT) also called glutamate pyruvate transaminase (GPT) : - It catalyzes the transfer of amino group of alanine to a-ketoglutarate resulting in formation of pyruvate and L-glutamate Q.ALTL-Alanine Q+ a-ketoglutarate Q _____ Pyruvate Q + L-glutamate Q PLPAspaate transaminase (AST) also called glutamate oxaloacetate transaminase (GOT) : It catalyzes the transfer of amino group of aspaate to a-ketoglutarate resulting in formation of oxaloacetate and L-glutamate.ASTL-Aspaate + a-ketoglutarate Oxaloacetate + L-glutamate PLPMost amino acids undergo transamination reaction except lysine, threonine, proline and hydroxyproline.All the amino groups from amino acids that undergo transamination are collected into one common amino acid, i.e., glutamate. This is impoant because L-glutamate is the only amino acid that undergoes oxidative deamination at an appreciable rate in mammalian tissue. Thus, formation of ammonia from amino acids occurs mainly the a-amino nitrogen of glutamate. Transamination is not restricted to a-amino groups. The 6-amino group of ornithine (but not the E-amino group of lysine) undergoes transmination.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now