All the following are true about transient tachypnea of newborn except
**Transient Tachypnea of Newborn (TTN)**
**Core Concept**
Transient tachypnea of newborn (TTN) is a benign, self-limiting respiratory condition that affects newborns, particularly those born at term or near term. It is characterized by an abnormality in the clearance of fetal lung fluid, leading to respiratory distress.
**Why the Correct Answer is Right**
TTN occurs due to the delayed clearance of fetal lung fluid, which is rich in surfactant. The excess fluid causes an increase in pulmonary vascular resistance, leading to tachypnea (rapid breathing rate). The condition is more common in newborns with maternal diabetes, cesarean delivery, and respiratory distress syndrome (RDS). The delayed clearance of fetal lung fluid is also associated with the immaturity of the lung's lymphatic system, which is responsible for draining excess fluid from the lungs.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because TTN is not a result of surfactant deficiency. In fact, TTN occurs in the presence of adequate surfactant levels.
**Option B:** This option is incorrect because TTN is not a chronic condition. It is a self-limiting condition that resolves on its own within 24-48 hours.
**Option C:** This option is incorrect because TTN is not caused by an infection. It is a benign, non-infectious condition.
**Option D:** This option is incorrect because TTN does not require oxygen therapy. In fact, supplemental oxygen may be contraindicated in TTN due to the risk of pulmonary edema.
**Clinical Pearl / High-Yield Fact**
A key clinical pearl to remember is that TTN is often associated with a history of cesarean delivery or maternal diabetes. This is because these factors can contribute to the delayed clearance of fetal lung fluid, leading to TTN.
**Correct Answer:** D. TTN does not require oxygen therapy.