Transfusion of stored blood causes: (Repeat)
**Core Concept**
The question pertains to the adverse effects of blood transfusion, specifically the consequences of storing blood for an extended period. The underlying principle involves the biochemical changes that occur in red blood cells (RBCs) and plasma components during storage, leading to potential transfusion reactions.
**Why the Correct Answer is Right**
Stored blood undergoes changes in its constituent parts, including a decrease in 2,3-bisphosphoglycerate (2,3-BPG) levels, which can lead to impaired oxygen delivery to tissues. Additionally, stored blood contains higher levels of potassium, which can cause hyperkalemia in the recipient. Furthermore, the storage solution can cause a decrease in the levels of coagulation factors, increasing the risk of bleeding post-transfusion.
**Why Each Wrong Option is Incorrect**
**Option A:** This option might be tempting, but it's not directly related to the consequences of blood storage. While hemolysis can occur due to various reasons, it's not a primary concern with stored blood.
**Option B:** Although citrate is an anticoagulant in blood storage, its primary function is to prevent clotting in the storage container, not a direct consequence of storing blood.
**Option C:** This option might be related to transfusion reactions, but it's not the most accurate answer in the context of stored blood.
**Clinical Pearl / High-Yield Fact**
When transfusing stored blood, it's essential to monitor the recipient's potassium levels and coagulation parameters to mitigate the risk of hyperkalemia and bleeding.
**Correct Answer: C. Impaired oxygen delivery to tissues due to decreased 2,3-bisphosphoglycerate (2,3-BPG) levels and increased risk of bleeding due to decreased coagulation factors.**