**Core Concept**
The Parkland formula is a widely used method for calculating the amount of fluid required for burn resuscitation. This formula estimates the total amount of fluid needed to maintain adequate urine output and prevent shock in burn patients. The Parkland formula involves calculating the total fluid requirement based on the percentage of body surface area (BSA) burned and the patient's weight.

**Why the Correct Answer is Right**
The Parkland formula is calculated as 4 mL/kg/% BSA burned x weight in kg. In this case, the patient has 80% BSA burned and weighs 50 kg. First, we calculate the total amount of fluid required: 4 mL/kg/% BSA burned x 50 kg x 80% = 16000 mL. Since this is the total amount required for the first 24 hours, we need to calculate the amount required for the first 8 hours. The Parkland formula recommends administering half of the total fluid in the first 8 hours. So, the amount of fluid required in the first 8 hours is 16000 mL / 2 = 8000 mL.

**Why Each Wrong Option is Incorrect**
**Option A:** This option does not take into account the patient's weight and the percentage of BSA burned, making it an incorrect calculation.
**Option B:** This option does not use the Parkland formula correctly and does not consider the patient's weight and the percentage of BSA burned.
**Option C:** This option does not calculate the total fluid requirement correctly and does not consider the patient's weight and the percentage of BSA burned.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that the Parkland formula is only a guideline, and the actual fluid requirement may vary based on individual patient needs. Additionally, the formula assumes a normal body surface area, and adjustments may be needed for patients with altered body composition, such as those with obesity or edema.

**Correct Answer: D. 8000 mL.**