**Core Concept**
Transdermal patches are a type of drug delivery system that release medication through the skin and into the bloodstream. They are designed to provide a steady, controlled release of the active ingredient over a prolonged period. The choice of medication for transdermal delivery depends on its chemical properties, such as molecular weight, lipophilicity, and stability.

**Why the Correct Answer is Right**
Transdermal patches are commonly used for medications that are lipophilic, have a low molecular weight, and are stable in the presence of light and heat. They are particularly effective for treating conditions such as hypertension, pain, and hormone replacement therapy. However, some medications are not suitable for transdermal delivery due to their chemical properties or potential side effects.

**Why Each Wrong Option is Incorrect**
* **Option A:** This medication is not suitable for transdermal delivery due to its high molecular weight and poor penetration through the skin.
* **Option B:** This medication is not typically used in transdermal patches because it is highly water-soluble and has a short half-life.
* **Option C:** This medication is not commonly used in transdermal patches due to its potential for causing skin irritation and allergic reactions.

**Clinical Pearl / High-Yield Fact**
When selecting a medication for transdermal delivery, it's essential to consider its chemical properties, such as molecular weight, lipophilicity, and stability. This can help minimize potential side effects and ensure effective treatment.

**Correct Answer: C. Furosemide**