Toxic effects of high oxygen tension include all of the following except:
Correct Answer: Decreased cerebral blood flow
Description: The O2 toxicity seems to be due to the production of superoxide anion, which is a free radical and H2O2. One of the principal effects is to oxidize the polyunsaturated fatty acids that are essential components of many membranous structures of the cells. Another effect is to oxidize some of the cellular enzymes. Increased alveolar pO2 may lead to absorption atelectasis, damage to pulmonary capillaries and pulmonary edema. Oxygen toxicity also includes retinopathy of prematurity (in infants), convulsions and coma.
Category:
Physiology
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