Pathology Totipotency of embryonic stem cell is due to that they? A Can differentiate into all the tissues of embryonic or extraembryonic cell types. B Can differentiate into cells derived from any of the three germ layers. C Can differentiate only into cells of a closely related family D Can differentiate only in to one cell type 💡 Explanation Totipotency of embryonic stem cell is due to that they? ✓ Correct Answer: A. Can differentiate into all the tissues of embryonic or extraembryonic cell types.