Topical Mitomycin C is useful in treatment of?
Correct Answer: Tracheal stenosis
Description: Laryngotracheal stenosis treated by serial dilatation using Jackson bronchoscopes. Laser have tendency to recur and hence adjuvant methods are done to decrease the rate of restenosis. Mitomycin C is an example of one of these adjunctive agents. It is a chemical derived from the Streptomyces caespitosus bacterium. It is an alkylating agent which has both antineoplastic and antiproliferative propeies and inhibits fibroblast production and thus prevents restenosis.
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ENT
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