To rule out rheumatoid arthritis, most important among the followings is?
Correct Answer: HLA DR4
Description: DR4 is strongly associated with RA(also with Type 1 DM Pemphigus vulgaris).
Other options
HLA-B27 is associated with seronegative spondyloarthropathies (ankylosing spondylitis, Psoriatic arthritis, Reiter’s syndrome, reactive arthritis) and acute anterior uveitis
HLA DR8 is associated with Type 1 DM.
HLA DQ1 is associated with pemphigus vulgaris.
Category:
Pathology
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