**Core Concept**
Thromboxane A2 synthetase is an enzyme involved in the synthesis of thromboxane A2, a potent vasoconstrictor and platelet aggregator. Inhibiting this enzyme can prevent platelet aggregation and reduce thrombus formation.
**Why the Correct Answer is Right**
Thromboxane A2 synthetase inhibitors, such as dazoxiben, block the conversion of prostaglandin H2 to thromboxane A2 in platelets. This action prevents platelet activation and aggregation, which is essential in preventing thrombotic disorders. Thromboxane A2 synthetase inhibitors work by competing with prostaglandin H2 for the active site on the enzyme, thereby inhibiting its activity.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it does not accurately represent a thromboxane A2 synthetase inhibitor.
**Option B:** This option is incorrect as it is not a known inhibitor of thromboxane A2 synthetase. In fact, it may even have a pro-thrombotic effect.
**Option C:** This option is incorrect as it is not a specific inhibitor of thromboxane A2 synthetase, but rather a more general antiplatelet agent.
**Clinical Pearl / High-Yield Fact**
Thromboxane A2 synthetase inhibitors are a class of medications that can be used to prevent thrombotic disorders, such as myocardial infarction and stroke, particularly in patients with a history of these conditions.
**Correct Answer: D. Dazoxiben**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.