Thrombotic thrombocytopenic purpura is a syndrome characterized by –
Correct Answer: Thrombocytopenia, anemia, neurological abnormalities, progressive renal failure and fever
Description: Ans. is 'd' i.e., Thrombocytopenia, anemia, neurological abnormalities, progressive renal failureand fever o Thrombotic thrombocytopenic purpura is a disorder of 1vessel wall' characterised by lesions in arteriolar walls in various organs that initiate formation of localised platelet thrombi and fibrin deposits at various sites.Clinical pentad of TTPo Microangiopathico Thrombocytopeniao Decreased renalo Disturbed neuro-o FeverHemolytic(due to consumptionfunction (duelogical function Anemia (Coomb's negative)of platelets)deposits in theCharacteristically # HaemolysisRenaland non focal e.g.diffuse # Fragmentation of RBC'sVasculature).# Confusion # Increased LDH (elevated # Aphasia due to intra-vascular # Alteration in hemolysis) consciousness Testes of coagulation are generally normal :-o Normal PTo Normal APTTo Normal Fibrinogen concentrationo Normal Fibrin degradation products
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now