Dose of thiopentone used is
**Core Concept**
Thiopentone, also known as thiopental, is a barbiturate used for inducing general anesthesia. Its dose is critical for effective induction while minimizing the risk of adverse effects. The dose of thiopentone is determined by the patient's weight and the desired level of anesthesia.
**Why the Correct Answer is Right**
The dose of thiopentone typically ranges from 3 to 7 mg/kg, administered intravenously over 20-30 seconds. This rapid onset of action is due to the high lipid solubility of thiopentone, which allows it to quickly cross the blood-brain barrier. The correct dose is crucial to avoid excessive sedation, respiratory depression, or even cardiac arrest. The desired effect is a deep level of anesthesia, which is achieved when the patient's EEG shows a burst suppression pattern.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the dose of thiopentone is not dependent on the patient's age, but rather on their weight.
**Option B:** This option is incorrect because the dose of thiopentone is not typically adjusted based on the patient's renal function, as it is primarily metabolized in the liver.
**Option C:** This option is incorrect because the dose of thiopentone is not directly correlated with the patient's height, but rather with their weight.
**Clinical Pearl / High-Yield Fact**
A memorable point to keep in mind is that thiopentone's lipid solubility is the key factor contributing to its rapid onset of action. This is why it is often used for emergency situations requiring rapid anesthesia.
**Correct Answer: C. 5 mg/kg, 3-7 mg/kg**