Biochemistry Thiamine deficiency in a chronic alcoholic can reduce energy production as a result of which of the following reasons? A It is required for the process of transamination B It is a co-factor for oxidative reduction C It is a co-enzyme for transketolase in pentose phosphate pathway D It is a co-enzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase in TCA pathway 💡 Explanation Thiamine deficiency in a chronic alcoholic can reduce energy production as a result of which of the following reasons? ✓ Correct Answer: D. It is a co-enzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase in TCA pathway