Thiamine deficiency decreases cellular metabolism because:
Correct Answer: Thiamine is a coenzyme for pyruvate dehydrogenase and alfa-ketoglutarate dehydrogenases
Description: Thiamine deficiency results in decreased energy production because TPP interferes with its coenzyme for pyruvate and alphaketoglutarate dehydrogenase.Chronic peripheral Neuritis, Beriberi & Wemicke Encephalopathy with Korsakoff's Psychosis.Thiamin requirements increase in excess intake of carbohydrates and its deficiency leads to decreased energy production
Category:
Biochemistry
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