Biochemistry Thiamine deficiency causes lactic acidosis due to defect in the action of? A Alpha - KG dehydrogenase B Sorbitol reductase C Lactate dehydrogenase D Pyruvate dehydrogenase 💡 Explanation Thiamine deficiency causes lactic acidosis due to defect in the action of? ✓ Correct Answer: D. Pyruvate dehydrogenase