Biochemistry The velocity-substrate curve below characterizes an allosteric enzyme system. The curve demonstrates that: A A modifier changes the binding constant for the substrate but not the velocity of the reaction B A modifier binding to the allosteric site can also affect the catalytic site C Binding of the substrate is independent of its concentration D Binding of the modifier is independent of its concentration 💡 Explanation The velocity-substrate curve below characterizes an allosteric enzyme system. The curve demonstrates that: ✓ Correct Answer: B. A modifier binding to the allosteric site can also affect the catalytic site