**Core Concept**
Methyldopa is a centrally acting antihypertensive agent that works by stimulating alpha-2 adrenergic receptors in the brain, leading to a decrease in sympathetic outflow and a subsequent reduction in blood pressure.

**Why the Correct Answer is Right**
Methyldopa is primarily used to treat hypertension, including essential hypertension and hypertension associated with renal disease. It is also used to manage symptoms of Parkinson's disease due to its ability to reduce tremors and rigidity. Additionally, methyldopa has been used in pregnancy-induced hypertension, particularly in the second and third trimesters.

**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because methyldopa is not typically used to treat heart failure. Its primary mechanism of action is not to increase cardiac contractility or reduce fluid overload, but rather to decrease sympathetic tone.
**Option B:** Incorrect because methyldopa is not an alternative to beta-blockers in the management of hypertension. While both classes of medications can lower blood pressure, they work through different mechanisms.
**Option C:** Incorrect because methyldopa is not used to treat acute hypertension. Its onset of action is too slow, and it is typically used as a long-term management option.

**Clinical Pearl / High-Yield Fact**
Methyldopa is a good example of a medication that can cause a positive Coombs test, indicating the presence of autoantibodies against red blood cells. This is a rare but important side effect that clinicians should be aware of.

**Correct Answer: A. Methyldopa is not typically used to treat heart failure.**