Pharmacology The unique property of SERMs is that they: A Have both estrogenic and progestational agonistic activity B Inhibits the aromatase enzyme that is required for estrogen synthesis C Produces estrogenic effect without binding to estrogen receptors D Act as agonist in some tissues and antagonist in other tissues 💡 Explanation The unique property of SERMs is that they: ✓ Correct Answer: D. Act as agonist in some tissues and antagonist in other tissues