The type of mammary ductal carcinoma in situ (DCIS) most likely to result in a palpable abnormality in the breast is –
Correct Answer: Comedo DCIS
Description: Carcinoma of the breast is divided into :
Carcinoma in situ → neoplastic cells is limited to ducts and lobules by the basement membrane.
Invasive carcinoma (infiltrating carcinoma) → cells invade beyond the basement membrane.
Caricnoma in situ :
It is of two types
A. Ductal carcinoma insitu (DCIS, intraductal carinoma )
Most frequently present as manzmographic calcification.
Rarely palpable mass may also occur in comedocarcinoma.
DCTS is of two types -
i. Comedocarcinoma
ii. Noncomedo DCTS → Solid, cribriform, papillary or micropapillary
B. Lubular carcinoma in Situ (LCIS)
Always an incidental finding in a biopsy performed for another reason.
LCIS is not associated with calcification → Therefore, it remains infrequent with or without mammography (in contrast to DCIS)
Frequently multicentric and bilateral
Signet ring cells are common.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now