The type of Diphtheria with highest mortality is
**Core Concept**
Diphtheria is a bacterial infection caused by Corynebacterium diphtheriae, characterized by the formation of a pseudomembrane in the throat and potential life-threatening complications. The type of diphtheria with the highest mortality is determined by the presence of a specific toxin.
**Why the Correct Answer is Right**
The toxin responsible for the severity of diphtheria is diphtheria toxin, which is produced by the bacteria. The toxin works by inhibiting protein synthesis in host cells, leading to cell death and tissue damage. The presence of the diphtheria toxin is a key factor in determining the severity of the disease. In particular, the toxin can cause cardiac and neurological complications, which are associated with high mortality rates.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify the toxin responsible for the severity of diphtheria.
**Option B:** This option is incorrect because it does not accurately describe the type of diphtheria with the highest mortality.
**Option C:** This option is incorrect because it does not provide a clear explanation for the high mortality rate associated with this type of diphtheria.
**Clinical Pearl / High-Yield Fact**
The presence of the diphtheria toxin is a key factor in determining the severity of the disease, and the toxin can cause cardiac and neurological complications, which are associated with high mortality rates.
**Correct Answer:** C. Toxinogenic diphtheria.