Pharmacology The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by : A Inhibitory action of the unabsorbed drug on the abnormal colonic flora B Breakdown of the drug in colon to release 5–amino-salicylic acid which suppresses inflammation locally C Release of sulfapyridine having antibacterial property D Systemic immunomodulatory action of the drug 💡 Explanation The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by : ✓ Correct Answer: B. Breakdown of the drug in colon to release 5–amino-salicylic acid which suppresses inflammation locally