The target antigen in dermolytic variant of epidermolysis bullosa is:
Correct Answer: Collagen 7
Description: Epidermolysis bullosa is classified into 4 types depending on the level of cleavage: 1. Epidermolytic variant : Keratin 5 & 14 (most common antigen) 2. Lamina lucida lytic : Laminin 5 (most common antigen) 3. Dermolytic variant : Type 7 collagen (most common antigen) 4. Mixed variant : Kindlin-1 (most common antigen) Ref: Rook's Textbook of Dermatology, 8th Edition, Page 39.2.
Category:
Skin
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