Physiology The site at which 1,25-hydroxylation of Vitamin-D takes place in the kidneys is: A Collecting ducts B Glomerulus C Proximal convoluted tubules D Distal convoluted tubules 💡 Explanation The site at which 1,25-hydroxylation of Vitamin-D takes place in the kidneys is: ✓ Correct Answer: C. Proximal convoluted tubules