Physiology The sigmoid nature of Hb-02 dissociation curve is because of A Binding of one 02 molecule increase the affinity for the next 02 molecule. B Alpha chain has more affinity for 02 than beta chain C Beta chain has more affinity for 02 than alpha chain D Haemoglobin in acidic in nature 💡 Explanation The sigmoid nature of Hb-02 dissociation curve is because of ✓ Correct Answer: A. Binding of one 02 molecule increase the affinity for the next 02 molecule.