Physiology The RBC in beta-thalassemia are typically: A Microcytic and hypochromic. B Microcytic and normochromic. C Normocytic and normochromic. D Macrocytic and hypochromic. 💡 Explanation The RBC in beta-thalassemia are typically: ✓ Correct Answer: A. Microcytic and hypochromic.