Physiology The production of estradiol by the testes requires: A Sertoli cell follistatin B LH and Leydig cells C Activin but not LH D Leydig cell, Sertoli cells, LH, and FSH 💡 Explanation The production of estradiol by the testes requires: ✓ Correct Answer: D. Leydig cell, Sertoli cells, LH, and FSH