The probable diagnosis in a patient with below given flow volume loop after spirometry?
Correct Answer: Myasthenia gravis
Description: The probable diagnosis in this patient based on restrictive pattern in the flow volume loop is Myasthenia gravis Features of the flow volume loop above: Decreased TLC and Vital capacity Residual volume is elevated. Because of which loop is shifted to right side(Normally it is present in the center) All the above features are seen in restrictive type of lung disease Myasthenia gravis In it, Both lung recoil and passive chest wall recoil are normal. Respiratory muscle strength is insufficient to push the passive respiratory system fully toward either volume extreme Because of reduced muscle strength MG presents with restrictive pattern on flow volume loop. =Obstructive flow pattern seen in: Asthma, Emphysema, Endobronchial neoplasm.
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