Biochemistry The presence of a noncompetitive inhibitor can be implicated in which of the outcome? A Leads to both an increase in the Vmax of a reaction and an increase in the Km B Leads to a decrease in the observed Vmax C Leads to a decrease in Km and Vmax D Leads to an increase in Km without affecting Vmax π‘ Explanation The presence of a noncompetitive inhibitor can be implicated in which of the outcome? β Correct Answer: B. Leads to a decrease in the observed Vmax