Pharmacology The positive inotropic effect of digitalyzers is due to invitation of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to A Decrease the activity of Na+/Ca+ exchanger causing decrease the influx of sodium and decreased efflux of Ca++ in the sarcolemma B Decreased efflux of Na+ leading to less negative resting membrane potential and opening of voltage gated Ca+ + channels on the T tubules C Increased intracellular Na+ causing increased efflux of any place and increase the influx of Ca + + through Na+/ Ca + + exchanges in sarcolemma D Increased intracellular Na+ decreasing the activity of Ca + + pump in the sarcoplasmic reticulum 💡 Explanation The positive inotropic effect of digitalyzers is due to invitation of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to ✓ Correct Answer: A. Decrease the activity of Na+/Ca+ exchanger causing decrease the influx of sodium and decreased efflux of Ca++ in the sarcolemma