**Core Concept**
Corrosive acids in the stomach can cause severe damage to the mucosal lining, leading to ulceration and perforation. The pathways followed by corrosive acids in the stomach are crucial in understanding the pathophysiology of this condition.
**Why the Correct Answer is Right**
The pathways followed by corrosive acids in the stomach involve the initial penetration of the acid into the mucosal lining, followed by the activation of various enzymes and inflammatory mediators. The acid penetrates the mucosa through the tight junctions between epithelial cells, causing coagulative necrosis and ulceration. The activated enzymes, such as trypsin and chymotrypsin, further exacerbate the damage by breaking down the mucosal proteins. The inflammatory response is triggered by the release of cytokines and chemokines, leading to increased permeability and edema.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is a distractor and does not describe a known pathway followed by corrosive acids in the stomach.
* **Option B:** This option is incorrect because it refers to the pathway followed by alkaline substances, not corrosive acids.
* **Option C:** This option is incorrect because it is a distractor and does not accurately describe the pathways followed by corrosive acids in the stomach.
**Clinical Pearl / High-Yield Fact**
The "lethal triad" of corrosive acid ingestion includes metabolic acidosis, hypovolemic shock, and coagulopathy, which can lead to multi-organ failure if not promptly treated.
**Correct Answer: B. Transmucosal diffusion.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.