Surgery The occurrence of hypothyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goiter is known as: A Jod-Basedow effect B Wolff-Chaikoff effect C Rafetoff Syndrome D Pendred Syndrome 💡 Explanation The occurrence of hypothyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goiter is known as: ✓ Correct Answer: B. Wolff-Chaikoff effect